our  previous  studies demonstrated  the  preventive effect  of  nigella  sativa  extract  on asthma and water-soluble substances of this extract, especially its methanol fraction were responsible for this relaxation on contracted tracheal chains of guinea pigs. for the first time, the present study has been conducted to determine the main constituents of its methanolic extract. four constituen...

Berberis integerrima is a member of Berberidaceae family. Berberine is one of the main constituents of this plant, having neuroprotective effect on central nervous system diseases. In this study, the anticonvulsant activity of methanolic extract, and hydromethanolic fraction, and chloroform fraction of B integerrima was assessed. The anticonvulsant effect of B integerrima was investigated using...

objective: phototoxicity is a kind of dermatitis that is activated by exposure to ultraviolet light following the administration of some drugs or natural products. artemia salina (a. salina) (brine shrimp) has been effectively applied for toxicity testing and is perfect for biological screening of many chemicals for simultaneous evaluation of toxicity and phototoxicity. the objective of this st...

Objective: Phototoxicity is a kind of dermatitis that is activated by exposure to ultraviolet light following the administration of some drugs or natural products. Artemia salina (A. salina) (brine shrimp) has been effectively applied for toxicity testing and is perfect for biological screening of many chemicals for simultaneous evaluation of toxicity and phototoxicity. The objective of this st...

BACKGROUND Mungbean [Vigna radiata (L.) Wilczek] is an important pulse crop globally. This imperative crop is severely affected by charcoal rot disease caused by Macrophomina phaseolina (Tassi) Goid. In the present study, the leaves of Calotropis procera L. were tested for their antifungal potential against M. phaseolina. MATERIALS AND METHODS Various concentrations i.e. 1%, 2.5%, 4%, 5.5% an...

this study was designed to examine the chemical composition and in-vitro antioxidant activity of the essential oil and methanolic extract of teucrium orientale subsp. taylori. the gc and gc–ms analysis of the essential oil resulted in determination of 40 components representing 96.4% of the oil. the major constituents of the oil were linalool (28.6%), caryophyllene oxide (15.6%), 1,8-cineol (4....

BACKGROUND Sphaeranthus amaranthoides commonly known as sivakaranthai is used in folklore medicine for the treatment of skin diseases. METHODS The antioxidant activity of the extract and its fraction was evaluated by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, total antioxidant capacity, and total phenolic content. The tested plant extracts showed variable de...

Phytochemical screening of various fractions of Datura alba showed bioactive secondary metabolites based on microbial and antioxidant activities. n-Hexane fraction showed a significant activity against three selected bacterial strains; Bacillus subtilis, Klebsiella pneumoniae and Staphylococcus aureus while other isolated fraction showed moderate activity. The ethyl acetate (88.89 %) and methan...

"Ethnopharmacological" use of roots of Boerhaavia diffusa (B. diffusa) in the treatment of epilepsy in Nigerian folk medicine and reports showing the presence of a calcium channel antagonistic compound "liriodendrin" in its roots, led us to undertake the present study. The study was designed to investigate the methanolic root extract of B. diffusa and its different fractions including liriodend...

background: due to multiple drug resistance against antimicrobial drugs for treatment of infectious disease, investigations to discovering new antibacterial compounds from natural sources have been designated. objective: according to antimicrobial effects of some capparis species, this study was carried out to evaluate the antimicrobial activity of the extract and fractions of capparis cartilag...